Titans vs. Panthers Predictions – NRL Round 22 2025

We have Titans vs. Panthers predictions for the Round 22 game on Saturday August 2 at 3:00pm at Cbus Super Stadium.

One of the hottest teams in the NRL are the Panthers, who have gone from struggling to being one of the premiership favourites.

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Titans vs. Panthers Predictions

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Best Bet

Panthers –12.5 @ $1.90

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The Panthers are red-hot after beating the Wests Tigers 36-2 last week, and their winning run is unlikely to stop at the hands of the Titans.

Gold Coast scored a good upset win over the Warriors, but producing back-to-back good games has proven tough for the Titans. They should struggle against a complete team in the Panthers, who have rocketed up the NRL ladder into fifth.

Covering a –12.5 line shouldn’t be too difficult considering the Titans lost to the Tigers two weeks ago. That game is the best form guide, so back the defending champions with confidence.

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Same Game Multi

Panthers –12.5, Brian To'o Anytime Try Scorer, Dylan Edwards Anytime Try Scorer, Under 47.5 @ $15.00

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Brian To’o hasn’t scored in his last four games for the Panthers, which is surprising, but we’re happy to stick with the quality winger.

He had a good State of Origin series for the Blues, and despite the winger not scoring for the Panthers, they’ve still managed to produce a winning streak. That could change on Saturday, so take the $1.78 odds.

We also like Dylan Edwards to score and under 47.5 points. Edwards has three tries from his last two games, and punters get value odds at $2.18. The under should also cash, given that they combined for only 30 points in their prior 2025 meeting.

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Best Value Bet

Nathan Cleary Anytime Try Scorer @ $3.50

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Nathan Cleary is best known for his kicking game close to the line, but he’s a capable try scorer if the defence rushes him.

He has two tries from his last three games, so the odds are generous considering his form. The best player in the NRL should get chances to score against a moderate Titans defence, so snap up the $3.50 odds.