EPL Week 21 Expert Tips & Predictions

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With cup competitions having dominated the landscape in English football for the past week or so, the cut and thrust of Premier League action returns in 2025. Liverpool allowed their title rivals the smallest glimmer of hope last weekend in drawing with Manchester United, but Arsenal and Chelsea couldn’t cash in behind them. Nottingham Forest remain the story of the season, entrenched in the top 4, whilst Newcastle are also starting to build some momentum. Southampton continue to tell a sorry tale down at the bottom of the pile, with problems mounting for Leicester City too.

Here are our Premier League tips for the next round of fixtures this season:

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EPL Week 21 Predictions

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Chelsea vs Bournemouth – Stamford Bridge

Chelsea ($1.67)

Bournemouth ($4.90)

Draw ($4.40)

Chelsea and Bournemouth clash in West London, with both sides looking to secure European football at the end of the campaign. Talk of winning the Premier League table has eased at Chelsea in recent weeks, following three games without a win and they need to get back on track here. Bournemouth have picked up some incredible results this season and are pushing to finish inside the top 8 or better come the end of the campaign. This will be closer than the odds suggest but Chelsea could just sneak over the line.

Betting tip: Chelsea to win the match ($1.67)

Chelsea to win 2-1

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Brentford vs Manchester City – Gtech Community Stadium

Brentford ($5.10)

Manchester City ($1.66)

Draw ($4.60)

Manchester City will be put to the test once again here, as they travel to Brentford in search of some consistency. The Bees have been going very well this term, particularly at home and there is a solidity to them under Thomas Frank in key areas. City have won their last two league games coming into this one, but problems remain at the Etihad, and they have been faltering hugely in games such as this. Brentford will fancy their chances here and they look a good price to bag a home win.

Betting tip: Brentford to win the match ($5.10)

Brentford to win 2-1

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West Ham United vs Fulham – London Olympic Stadium

West Ham United ($2.90)

Fulham ($2.45)

Draw ($3.60)

A London derby of sorts is on the agenda here, as West Ham host Fulham and both sides will be chasing important points in this one. Julen Lopategui is a man under serious pressure at West Ham and he needs the tide to start turning quickly. Meanwhile, Fulham are battling away under Marco Silva and are scoring and conceding goals in equal measure. This could be a chaotic encounter at the Olympic Stadium and a score draw could be on the cards.

Betting tip: The match to finish as a draw ($3.60)

2-2 Draw

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Nottingham Forest vs Liverpool – City Ground

Nottingham Forest ($4.90)

Liverpool ($1.73)

Draw ($4.10)

Nottingham Forest are firmly in the hunt in the Premier League title race and next up for them is a clash with leaders Liverpool. The Tricky Trees have surpassed all expectations this term and should be up for rattling into the Champions-elect in this one. It has been all about Arne Slot’s men this season though, who suffered their only defeat of the campaign to Forest back in September and they will be out for revenge here. Forest will huff and puff, but Liverpool should have too much for them.

Betting tip: Liverpool to win the match ($1.73)

Liverpool to win 2-0

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Leicester City vs Crystal Palace – King Power Stadium

Leicester City ($3.75)

Crystal Palace ($2.00)

Draw ($3.75)

Relegation threatened Leicester City take on Crystal Palace in this one, with both sides in need of a win down at the bottom of the table. The Foxes are finding form hard to come by under Ruud van Nistelrooy and look to be in a serious spot of bother. Crystal Palace meanwhile are beginning to improve under Oliver Glasner following a rough start to the campaign and they will see this as a winnable one on the road. This should be tight, but Crystal Palace should find a way to get the job done in the East Midlands.

Betting tip: Crystal Palace to win the match ($2.00)

Crystal Palace to win 2-1

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Everton vs Aston Villa– Goodison Park

Everton ($3.20)

Aston Villa ($2.30)

Draw ($3.40)

Everton continue to plug away under Sean Dyche, but their next assignment will be a tricky one against Aston Villa. The Toffees can’t seem to stretch away from relegation trouble this term and are now a side under a spot of pressure. Villa are in the hunt for a top 4 finish and have Champions League football to balance under Unai Emery, making this an important fixture. Goals could be hard to come by here, but Villa could just sneak over the line.

Betting tip: Aston Villa to win the match ($2.30)

Aston Villa to win 1-0

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Newcastle United vs Wolves – St James’s Park

Newcastle United ($1.38)

Wolves ($8.50)

Draw ($5.80)

High-flying Newcastle United put one foot in the Carabao Cup semifinals last time out and they will be looking to build on that here against Wolves. Eddie Howe has his side firing again, with some key men back from injury and they look to be ready to push for a top 4 spot at least this term. Wolves meanwhile have shown signs of improvement under Vitor Pereira and need to string some results together to climb away from relegation trouble. This should be all about Newcastle though, who should prevail here.

Betting tip: Newcastle United to win the match ($1.38)

Newcastle United to win 3-0

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Arsenal vs Tottenham – Emirates Stadium

Arsenal ($1.36)

Tottenham ($8.50)

Draw ($6.00)

The North London derby is always hotly contested, and the prospect of Arsenal and Tottenham meeting here is a tantalising one. The Gunners have looked a little off colour in recent games and their 2-0 loss to Newcastle United in the Carabao Cup will be a great concern for Mikel Arteta and his men. That said, Tottenham have been off the pace all season and look to be in a real funk in the bottom half of the table under Ange Postecoglou. This could be another goal fest, with Arsenal most likely to get the job done.

Betting tip: Arsenal to win the match ($1.36)

Arsenal to win 4-2

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Ipswich Town vs Brighton – Portman Road

Ipswich Town ($4.10)

Brighton ($1.95)

Draw ($3.80)

Ipswich have been digging in recently, looking to forge a path up the Premier League table and a meeting with Brighton promises to be a good one here. The Tractor Boys are finding ways to score plenty of goals in the top flight but they are conceding heaps too and they have won just 1 game at home this term. Brighton meanwhile picked up a good point against Arsenal last weekend, a result they will be looking to take heart from heading into this one. This could be another entertaining one, with Brighton perhaps the most likely.

Betting tip: Brighton to win the match ($1.95)

Brighton to win 3-1

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Manchester United vs Southampton – Old Trafford

Manchester United ($1.32)

Southampton ($10.00)

Draw ($6.10)

Lowly Southampton look to be on the cusp of dropping back into the Championship and things won’t get too much easier here against Manchester United. The Red Devils have been slipping into the relegation picture themselves but a good point at Anfield last weekend will give them some serious hope. Southampton meanwhile are a side who look out of their depth in the Premier League, and they have some serious work to do to preserve their top flight status. Manchester United couldn’t have asked for a better game here and should pick up three midweek PL points.

Betting tip: Manchester United to win the match ($1.32)

Manchester United to win 3-0

EPL Week 21 multi bet

We’re backing four results this week as an accumulator with a betting stake of $50:

Newcastle United vs Wolves – Newcastle United
Nottingham Forest vs Liverpool – Liverpool
Manchester United vs Southampton – Manchester United
Arsenal vs Tottenham – Arsenal

A $50 wager would pay out $372.95 if successful at the current odds.

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All odds are with Picklebet Use Code: 'GOBET500'

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